Nature Communications (Oct 2022)

Alignment of single-cell trajectory trees with CAPITAL

  • Reiichi Sugihara,
  • Yuki Kato,
  • Tomoya Mori,
  • Yukio Kawahara

DOI
https://doi.org/10.1038/s41467-022-33681-3
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Global alignment of complex cell state trajectories between single-cell datasets remains challenging. Here, the authors present a computational method called CAPITAL to compare branching trajectories, and demonstrate that this method achieves accurate and robust alignments.