New Approach to Drug Discovery of a Safe Mitochondrial Uncoupler: OPC-163493

• Takashi Okamoto,
• Takahiro Shimada,
• Chiharu Matsumura,
• Hitomi Minoshima,
• Takashi Ban,
• Motohiro Itotani,
• Toshio Shinohara,
• Shigekazu Fujita,
• Satoshi Matsuda,
• Seiji Sato,
• Naohide Kanemoto

Affiliations

Takashi Okamoto

Department of Lead Discovery Research, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

Takahiro Shimada

Department of Drug Metabolism and Pharmacokinetics, Nonclinical Research Center, Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

Chiharu Matsumura

Medicinal Chemistry Research Laboratories, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

Hitomi Minoshima

Pharmaceutical Planning Group, Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan

Takashi Ban

Department of Renal and Cardiovascular Research, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

Motohiro Itotani

Quality Assurance Section (Tokushima Wajiki Factory), Quality Assurance Department, Headquarters for Product Safety and Quality Assurance, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

Toshio Shinohara

Medicinal Chemistry Research Laboratories, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

Shigekazu Fujita

Human Resources Department, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

Satoshi Matsuda

Administration Department, Diagnostic Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

Seiji Sato

Medicinal Chemistry Research Laboratories, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

Naohide Kanemoto

Department of Lead Discovery Research, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan