Accurate diagnosis and sub categorization of benign adenomyoepithelioma of the breast-tubular type: A challenge on core needle biopsy

Abstract

Adenomyoepithelioma (AME) is a biphasic myoepithelial tumor with poorly understood histogenesis. Most of these cases have a benign course. They can cause major diagnostic dilemmas, particularly on core needle biopsy. Here we report of a case of a benign adenomyoepithelioma in a fourty-four year old female who presented with hard breast lump, which highlights the diagnostic difficulties encountered on conventional histopathology and the importance of immunohistochemistry in differentiating them from their mimics.

Keywords

• breast
• calponin
• cytokeratin
• myoepithelial
• p63