Use of prasugrel in patients with clopidogrel hypersensitivity

Abstract

Allergic response to clopidogrel is a significant and difficult clinical problem as it is one of the recommended drugs after coronary stenting to prevent thrombosis. We present the case of a 57-year-old man who underwent coronary revascularization and developed an urticarial rash after being started on dual antiplatelet medication (aspirin and clopidogrel). He was managed conservatively, to which he responded well and was discharged on prasugrel. This case study from India adds to the available literature and discusses the alternative drugs that could be used in patients with clopidogrel hypersensitivity.

Keywords

• adverse drug reaction
• clopidogrel-induced hypersensitivity reaction
• hypersensitivity reaction
• urticarial rash