Nature Communications (Jul 2021)
The tectonigral pathway regulates appetitive locomotion in predatory hunting in mice
- Meizhu Huang,
- Dapeng Li,
- Xinyu Cheng,
- Qing Pei,
- Zhiyong Xie,
- Huating Gu,
- Xuerong Zhang,
- Zijun Chen,
- Aixue Liu,
- Yi Wang,
- Fangmiao Sun,
- Yulong Li,
- Jiayi Zhang,
- Miao He,
- Yuan Xie,
- Fan Zhang,
- Xiangbing Qi,
- Congping Shang,
- Peng Cao
Affiliations
- Meizhu Huang
- Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory)
- Dapeng Li
- Department of Neurobiology, School of Basic Medical Sciences, Beijing Key Laboratory of Neural Regeneration and Repair, Advanced Innovation Center for Human Brain Protection, Capital Medical University
- Xinyu Cheng
- Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences
- Qing Pei
- National Institute of Biological Sciences
- Zhiyong Xie
- National Institute of Biological Sciences
- Huating Gu
- National Institute of Biological Sciences
- Xuerong Zhang
- National Institute of Biological Sciences
- Zijun Chen
- State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences
- Aixue Liu
- Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences
- Yi Wang
- State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences
- Fangmiao Sun
- College of Life Sciences, Peking University
- Yulong Li
- College of Life Sciences, Peking University
- Jiayi Zhang
- State Key Laboratory of Medical Neurobiology, Fudan University
- Miao He
- State Key Laboratory of Medical Neurobiology, Fudan University
- Yuan Xie
- Key Laboratory of Neural and Vascular Biology in Ministry of Education, Department of Pharmacology, Hebei Medical University
- Fan Zhang
- Key Laboratory of Neural and Vascular Biology in Ministry of Education, Department of Pharmacology, Hebei Medical University
- Xiangbing Qi
- National Institute of Biological Sciences
- Congping Shang
- Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory)
- Peng Cao
- National Institute of Biological Sciences
- DOI
- https://doi.org/10.1038/s41467-021-24696-3
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 17
Abstract
Goal-oriented movement is a fundamental animal behaviour. Here, the authors show that neurons in the superior colliculus project to the substantia nigra pars compacta, regulating dopaminergic signaling and specifically appetitive locomotion in mice.
