Adaptive liquid interfaces induce neuronal differentiation of mesenchymal stem cells through lipid raft assembly

Xiaofang Jia; Jingwen Song; Wenyan Lv; Jonathan P. Hill; Jun Nakanishi; Katsuhiko Ariga

doi:10.1038/s41467-022-30622-y

Nature Communications (Jun 2022)

Adaptive liquid interfaces induce neuronal differentiation of mesenchymal stem cells through lipid raft assembly

Xiaofang Jia,
Jingwen Song,
Wenyan Lv,
Jonathan P. Hill,
Jun Nakanishi,
Katsuhiko Ariga

Affiliations

Xiaofang Jia: School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University
Jingwen Song: International Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS)
Wenyan Lv: School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University
Jonathan P. Hill: International Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS)
Jun Nakanishi: Research Center for Functional Materials, National Institute for Materials Science
Katsuhiko Ariga: International Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS)

DOI: https://doi.org/10.1038/s41467-022-30622-y
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 10

Abstract

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In this work the authors report how human mesenchymal stem cells rapidly adapt to dynamic microenvironment through lipid raft in membrane microdomains that direct neurogenesis.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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