Legends of DNA morphology.

Abstract

Background. It is believed that modern views on the structure of DNA molecules are based on the results of experiments that have an impeccable interpretation. This is not entirely correct, because the results of these experiments have more than one interpretation. Objective. Discussion of the correctness of the interpretation of the experimental results, on the basis of which the model of double-stranded DNA was proposed. Results. It is shown that modern views on the structure of DNA molecules are mainly determined by the ability of sodium salts to form fibers, as well as the ability of a curved glass to form fibers on its surface. In addition, an analysis of existing ideas on DNA melting and intercalation of aromatic dyes in its structure has been analyzed. Conclusion. The results of experiments on which modern ideas about the structure and properties of DNA molecules are based were poorly interpreted. For this reason, the models of double DNA spirals, which were the result of these interpretations, "function poorly". Thus, these DNA models do not allow satisfactory explanation of a number of properties of real DNA, including their melting. For this reason, the results of the experiments, on the basis of which the double-chain model of the DNA molecule is proposed, should receive a new interpretation that will make it possible to change the perception of the morphology of DNA molecules.

Keywords

• ДНК
• структура ДНК
• плавлення
• інтеркаляція