VSTM1 regulates monocyte/macrophage function via the NF-κB signaling pathway
Wang Xiao-Fei,
En-Zhou,
Li Dong-Jiu,
Mao Cheng-Yu,
He Qing,
Zhang Jun-Feng,
Fan Yu-Qi,
Wang Chang-Qian
Affiliations
Wang Xiao-Fei
Department of Cardiology, The Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Bao Shan, Shanghai 201900, People’s Republic of China
En-Zhou
Department of Cardiology, The Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Bao Shan, Shanghai 201900, People’s Republic of China
Li Dong-Jiu
Department of Cardiology, The Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Bao Shan, Shanghai 201900, People’s Republic of China
Mao Cheng-Yu
Department of Cardiology, The Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Bao Shan, Shanghai 201900, People’s Republic of China
He Qing
Department of Cardiology, The Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Bao Shan, Shanghai 201900, People’s Republic of China
Zhang Jun-Feng
Department of Cardiology, The Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, 280 Mo He Road, Bao Shan, Shanghai 201900, People’s Republic of China
Fan Yu-Qi
Department of Cardiology, The Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, 280 Mo He Road, Bao Shan, Shanghai 201900, People’s Republic of China
Wang Chang-Qian
Department of Cardiology, The Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, 280 Mo He Road, Bao Shan, Shanghai 201900, People’s Republic of China
V-set and transmembrane domain-containing protein 1 (VSTM1) is negatively correlated with inflammation. However, its effect on atherosclerosis (AS) remains largely unexplored. In this study, we aimed to assess the effect of VSTM1 on the biological function of human peripheral blood mononuclear cells /macrophages stimulated by oxidized low-density lipoprotein (ox-LDL).
