Activated protein C light chain provides an extended binding surface for its anticoagulant cofactor, protein S

• José A. Fernández,
• Xiao Xu,
• Ranjeet K. Sinha,
• Laurent O. Mosnier,
• Michel F. Sanner,
• John H. Griffin

Affiliations

José A. Fernández

Department of Molecular Medicine and Scripps Research Institute, La Jolla, CA

Xiao Xu

Department of Molecular Medicine and Scripps Research Institute, La Jolla, CA

Ranjeet K. Sinha

Department of Molecular Medicine and Scripps Research Institute, La Jolla, CA

Laurent O. Mosnier

Department of Molecular Medicine and Scripps Research Institute, La Jolla, CA

Michel F. Sanner

Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, CA

John H. Griffin

Department of Molecular Medicine and Scripps Research Institute, La Jolla, CA; John H. Griffin, Scripps Research Institute, MEM-180, 10550 N. Torrey Pines Rd, La Jolla, CA 92037;