Nature Communications (Oct 2018)
Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cells
- Joseph Jose Thottacherry,
- Anita Joanna Kosmalska,
- Amit Kumar,
- Amit Singh Vishen,
- Alberto Elosegui-Artola,
- Susav Pradhan,
- Sumit Sharma,
- Parvinder P. Singh,
- Marta C. Guadamillas,
- Natasha Chaudhary,
- Ram Vishwakarma,
- Xavier Trepat,
- Miguel A. del Pozo,
- Robert G. Parton,
- Madan Rao,
- Pramod Pullarkat,
- Pere Roca-Cusachs,
- Satyajit Mayor
Affiliations
- Joseph Jose Thottacherry
- National Centre for Biological Sciences (NCBS), Tata Institute of Fundamental Research (TIFR)
- Anita Joanna Kosmalska
- Institute for Bioengineering of Catalonia (IBEC)
- Amit Kumar
- Raman Research Institute
- Amit Singh Vishen
- National Centre for Biological Sciences (NCBS), Tata Institute of Fundamental Research (TIFR)
- Alberto Elosegui-Artola
- Institute for Bioengineering of Catalonia (IBEC)
- Susav Pradhan
- Raman Research Institute
- Sumit Sharma
- CSIR - Indian Institute of Integrative Medicine
- Parvinder P. Singh
- CSIR - Indian Institute of Integrative Medicine
- Marta C. Guadamillas
- Integrin Signalling Lab, Cell Biology & Physiology Program, Cell & Developmental Biology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)
- Natasha Chaudhary
- University of Queensland, Institute for Molecular Bioscience and Centre for Microscopy and Microanalysis
- Ram Vishwakarma
- CSIR - Indian Institute of Integrative Medicine
- Xavier Trepat
- Institute for Bioengineering of Catalonia (IBEC)
- Miguel A. del Pozo
- Integrin Signalling Lab, Cell Biology & Physiology Program, Cell & Developmental Biology Area, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)
- Robert G. Parton
- University of Queensland, Institute for Molecular Bioscience and Centre for Microscopy and Microanalysis
- Madan Rao
- National Centre for Biological Sciences (NCBS), Tata Institute of Fundamental Research (TIFR)
- Pramod Pullarkat
- Raman Research Institute
- Pere Roca-Cusachs
- Institute for Bioengineering of Catalonia (IBEC)
- Satyajit Mayor
- National Centre for Biological Sciences (NCBS), Tata Institute of Fundamental Research (TIFR)
- DOI
- https://doi.org/10.1038/s41467-018-06738-5
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 14
Abstract
Plasma membrane tension is an important factor that regulates many key cellular processes. Here authors show that a specific dynamin-independent endocytic pathway is modulated by changes in tension via the mechano-transducer vinculin.
