International Journal of General Medicine (Jan 2022)
Safety and Efficacy of Endoscopic Treatment of Solitary Gastric Neurofibroma
Abstract
Meihong Yu,1,2 Kaixuan Li,3 Deliang Liu,1,2 Yuyong Tan1,2 1Department of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People’s Republic of China; 2Research Center of Digestive Disease, Central South University, Changsha, Hunan, People’s Republic of China; 3Department of Urology, Xiangya Hospital of Central South University, Changsha, Hunan, People’s Republic of ChinaCorrespondence: Yuyong TanDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, No. 139 Middle Renmin Road, Changsha, Hunan, 410011, People’s Republic of ChinaTel +86-15116280621Fax +86-731-85533525Email [email protected] LiDepartment of Urology, Xiangya Hospital of Central South University, No. 87 Xiangya Road, Changsha, Hunan, 410008, People’s Republic of ChinaTel +86-15580027242Email [email protected]: The studies on solitary gastric neurofibroma (GN) consist of only individual case reports, with little data and relevant information. We aimed to summarize the clinical features, endoscopic features, imaging findings, and pathological features and study the safety and efficacy of endoscopic treatment of solitary GN.Patients and Methods: We retrospectively collected and analyzed clinical data of patients who underwent endoscopic treatment in Department of Gastroenterology of a well-known tertiary hospital from August 2007 to September 2019 and were accurately diagnosed as having solitary GN.Results: A total of 788 patients with gastric submucosal tumors underwent endoscopic treatment, among whom 11 patients were found to have solitary GNs. The incidence of solitary GNs was 1.4%. All 11 patients were treated with endoscopy. Five patients underwent endoscopic full-thickness resection (EFTR) and six patients underwent endoscopic submucosal excavation (ESE). The en bloc resection rate of the 11 lesions was 100.0%. The median endoscopic operation time was 80 minutes. Average length of hospital stay was 6.4 ± 1.6 days. The median follow-up time was 29 months. No recurrence, distant metastasis, or disease-related death occurred during the follow-up.Conclusion: EFTR and ESE can serve as feasible, safe, and effective treatments for solitary GN.Keywords: endoscopic full-thickness resection, endoscopic submucosal excavation, gastric, neurofibroma, solitary
