Annals of Urologic Oncology (Mar 2024)

Research Progress of Metabolic Syndrome and Renal Cancer

  • Yiwen Wang,
  • Yajun Shi,
  • Mengye Zhang,
  • Jiao Cao

DOI
https://doi.org/10.32948/auo.2024.03.24
Journal volume & issue
Vol. 7, no. 1
pp. 26 – 32

Abstract

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Metabolic syndrome (MS) is a condition of metabolic abnormalities in genetically predisposed individuals that are caused by lifestyle habits such as consumption of diet rich in fat and lack of exercise. Few major symptoms include abnormal glucose tolerance, hypertension, abnormal lipid metabolism (including high triglycerides in the blood, low high density lipoprotein cholesterol, etc.), obesity, etc. Although metabolic syndrome has been found to be mainly related to cardiovascular diseases, diabetes, malignancy and other diseases, in recent years, more and more evidence has shown that MS is closely related to the occurrence, development and prognosis of kidney cancer, among which obesity and hypertension have been identified as major risk factors for kidney cancer. This article reviews the research progress on the relationship between MS and its components and the risk, invasiveness, and prognosis of renal carcinoma, so as to provide reference for the prevention, diagnosis, treatment and prognosis of renal cancer.

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