Communications Biology (Sep 2022)

Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment

  • Şükrü B. Demiral,
  • Peter Manza,
  • Erin Biesecker,
  • Corinde Wiers,
  • Ehsan Shokri-Kojori,
  • Katherine McPherson,
  • Evan Dennis,
  • Allison Johnson,
  • Dardo Tomasi,
  • Gene-Jack Wang,
  • Nora D. Volkow

DOI
https://doi.org/10.1038/s42003-022-03979-5
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 10

Abstract

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PET imaging in human participants revealed that D1 and D2 dopamine receptor availability was associated with eye-blink rates following treatment with oral methylphenidate, but not a placebo.