Frontiers in Neurology (Nov 2022)
Vestibular evoked myogenic potential may predict the hearing recovery in patients with unilateral idiopathic sudden sensorineural hearing loss
- Min Liang,
- Min Liang,
- Min Liang,
- Hui Wu,
- Hui Wu,
- Hui Wu,
- Jianyong Chen,
- Jianyong Chen,
- Jianyong Chen,
- Qin Zhang,
- Qin Zhang,
- Qin Zhang,
- Shuna Li,
- Shuna Li,
- Shuna Li,
- Guiliang Zheng,
- Guiliang Zheng,
- Guiliang Zheng,
- Jingchun He,
- Jingchun He,
- Jingchun He,
- Xiangping Chen,
- Xiangping Chen,
- Xiangping Chen,
- Maoli Duan,
- Maoli Duan,
- Jun Yang,
- Jun Yang,
- Jun Yang,
- Yulian Jin,
- Yulian Jin,
- Yulian Jin
Affiliations
- Min Liang
- Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Min Liang
- Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Min Liang
- Shanghai Key Laboratory of Translational Medicine on Ear and Nose Disease, Shanghai, China
- Hui Wu
- Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Hui Wu
- Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Hui Wu
- Shanghai Key Laboratory of Translational Medicine on Ear and Nose Disease, Shanghai, China
- Jianyong Chen
- Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Jianyong Chen
- Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Jianyong Chen
- Shanghai Key Laboratory of Translational Medicine on Ear and Nose Disease, Shanghai, China
- Qin Zhang
- Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Qin Zhang
- Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Qin Zhang
- Shanghai Key Laboratory of Translational Medicine on Ear and Nose Disease, Shanghai, China
- Shuna Li
- Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Shuna Li
- Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Shuna Li
- Shanghai Key Laboratory of Translational Medicine on Ear and Nose Disease, Shanghai, China
- Guiliang Zheng
- Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Guiliang Zheng
- Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Guiliang Zheng
- Shanghai Key Laboratory of Translational Medicine on Ear and Nose Disease, Shanghai, China
- Jingchun He
- Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Jingchun He
- Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Jingchun He
- Shanghai Key Laboratory of Translational Medicine on Ear and Nose Disease, Shanghai, China
- Xiangping Chen
- Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Xiangping Chen
- Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Xiangping Chen
- Shanghai Key Laboratory of Translational Medicine on Ear and Nose Disease, Shanghai, China
- Maoli Duan
- Department of Otolaryngology-Head and Neck Surgery, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden
- Maoli Duan
- Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden
- Jun Yang
- Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Jun Yang
- Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Jun Yang
- Shanghai Key Laboratory of Translational Medicine on Ear and Nose Disease, Shanghai, China
- Yulian Jin
- Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Yulian Jin
- Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- Yulian Jin
- Shanghai Key Laboratory of Translational Medicine on Ear and Nose Disease, Shanghai, China
- DOI
- https://doi.org/10.3389/fneur.2022.1017608
- Journal volume & issue
-
Vol. 13
Abstract
ObjectiveThis study investigates the association between vestibular function and prognosis in patients with unilateral idiopathic sudden sensorineural hearing loss (UISSNHL).DesignA retrospective analysis of 64 patients with UISSNHL was performed. Pure tone audiometry and vestibular function tests for otoliths and semicircular canals were performed to assess the influence of vestibular functional status on the outcome of patients with UISSNHL.ResultsPatients with abnormal cervical vestibular evoked myogenic potential (cVEMP) or ocular vestibular evoked myogenic potential (oVEMP) responded less favorably to treatment. In the ineffective group, cVEMP was normal in four patients (6.3%) and oVEMPs in three (4.7%). Meanwhile, cVEMP was abnormal in 32 patients (50.0%) and oVEMP in 33 (51.6%). Better hearing recovery occurred in those with normal cVEMP (33.76 ± 15.07 dB HL improvement) or oVEMP (32.55 ± 19.56 dB HL improvement), but this was not the case in those with normal caloric tests. Patients with abnormalities in both cVEMP and oVEMP were less responsive to treatment and had worse hearing recovery than those with normal results in only one of the two tests.ConclusionAbnormal oVEMP and/or cVEMP results indicate poor auditory outcomes in patients with UISSNHL. Patients with impaired otolith organ function are likely to have a larger and more severe pathological change in their inner ear.
Keywords
- unilateral idiopathic sudden sensorineural hearing loss
- vestibular function
- vestibular evoked myogenic potential
- caloric test
- otolith organ
- sacculus
