Journal of Infection and Public Health (Dec 2010)

A case of recurrent benign lymphocytic (Mollaret's) meningitis and review of the literature

  • P.J. Poulikakos,
  • E.E. Sergi,
  • A.S. Margaritis,
  • A.G. Kioumourtzis,
  • G.D. Kanellopoulos,
  • P.K. Mallios,
  • D.J. Dimitrakis,
  • D.J. Poulikakos,
  • A.A. Aspiotis,
  • A.D. Deliousis,
  • C.P. Flevaris,
  • A.K. Zacharof

Journal volume & issue
Vol. 3, no. 4
pp. 192 – 195

Abstract

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Summary: Mollaret's meningitis is a rare form of benign recurrent aseptic meningitis first described in 1944. We report a case of Mollaret's meningitis due to Herpes Simplex Virus type 2 (HSV2), diagnosed with Polymerase Chain Reaction (PCR) implementation in the Cerebrospinal fluid (CSF) of the patient and treated successfully with acyclovir. To our knowledge, this is the first case of Mollaret's meningitis reported in Greece. We reviewed the literature since PCR has become widely available. Herpes Simplex Virus type 2 has been the most commonly identified causative agent of Mollaret's meningitis. Keywords: Recurrent meningitis, Recurrent benign lymphocytic meningitis, Mollaret's meningitis, Herpes Simplex Virus, Herpetic meningitis