USING VAGINAL SELF-SAMPLING DEVICES FOR DETECTION OF HIGH-RISK HUMAN PAPILLOMAVIRUS

Abstract

The identification of cerval intraepithelial neoplasia is of crucial importance for reducing both incidence and mortality of cervical cancer. Currently, screening programs relying on Papanicolaou test or liquid-based cytology are employed in many countries but have a limited efficiency. Recently, HPV genotyping was suggested as a possible screening alternative as high-risk HPV strains are detected in almost all cervical cancer biopsies. Importantly, in addition to high sensitivity, efficient screening approach also requires a wide population coverage. As the main reasons for cervical cancer screening avoidance include fear of examination, embarrassment, and lack of time, self-sampling devices have the potential to significantly improve screening coverage. Such an approach implies invitation for gynecological examination only if high-risk HPV strains would be detected in the self-collected sample. Epidemiological studies demonstrated that results of HPV genotyping in self- and physician-collected samples are comparable; hence, self-sampling devices can be considered for the implementation in cervical cancer screening.

Keywords

• вирус папилломы человека
• скрининг
• рак шейки матки
• qvintip
• human papilloma virus
• screening
• cervical cancer
• qvintip