αE-catenin deletion in skeletal stem and progenitor cells (SSPCs) increases their adipogenic potential and protects against diet- or age-induced obesity and hyperglycemia

• Karen De Samblancx,
• Marion Mesnieres,
• Dana Trompet,
• Naomi Dirckx,
• Katrien Corbeels,
• Elena Nefyodova,
• Ruben Cardoen,
• Jolanda van Hengel,
• Frans van Roy,
• Greetje Vande Velde,
• Bart Van der Schueren,
• Chantal Mathieu,
• Christa Maes

Affiliations

Karen De Samblancx

Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), KU Leuven, Leuven, Belgium; Corresponding author.

Marion Mesnieres

Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), KU Leuven, Leuven, Belgium

Dana Trompet

Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), KU Leuven, Leuven, Belgium

Naomi Dirckx

Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), KU Leuven, Leuven, Belgium

Katrien Corbeels

Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium

Elena Nefyodova

Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), KU Leuven, Leuven, Belgium

Ruben Cardoen

Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), KU Leuven, Leuven, Belgium

Jolanda van Hengel

Department of Biomedical Molecular Biology, Ghent University; Inflammation Research Center, Flanders Institute for Biotechnology (VIB), Ghent, Belgium

Frans van Roy

Department of Biomedical Molecular Biology, Ghent University; Inflammation Research Center, Flanders Institute for Biotechnology (VIB), Ghent, Belgium

Greetje Vande Velde

Molecular Small Animal Imaging Center (MoSAIC), Department of Imaging & Pathology, KU Leuven, Leuven, Belgium

Bart Van der Schueren

Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium

Chantal Mathieu

Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium

Christa Maes

Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), KU Leuven, Leuven, Belgium