Journal of Clinical and Diagnostic Research (Sep 2019)
Cutaneous Plexiform Schwannoma of the Digit- A Case Report
Abstract
A common mimicker of Plexiform Neurofibroma (PN), Plexiform Schwannoma (PS) can occur sporadically and in weak association with NF2. It is important to differentiate between the two, as recurrence and malignant potential are common with PN requiring extensive surgery and rigorous follow-up. Though light microscopic features of PN and PS overlap especially in small biopsies, IHC with S-100 would help. S-100 immunostaining is diffuse and strong in PS while weak and patchy in PN. A rare case of cutaneous PS in the right index finger of a nine-year-old boy where S-100 immunostaining helped to confirm the diagnosis is hereby reported.
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