Research progress on PI3K/Akt signaling pathway and cerebral hemorrhage

Abstract

As a classic cell signal transduction pathway, PI3K/Akt pathway plays a role in a variety of biological processes, such as cell growth, proliferation, differentiation and apoptosis. As a kind of cerebrovascular disease with high disability and high mortality, the role of this signaling pathway in the incidence and development of cerebral hemorrhage has attracted more and more attention. In this article, the PI3K/Akt signal pathway was regarded as the main topic to analyze the structural and biological characteristics of this pathway, its relationship with cerebral hemorrhage and review the efficacy of drugs for cerebral hemorrhage based on the PI3K/Akt signaling pathway, aiming to provide novel ideas for the clinical treatment of cerebral hemorrhage.

Keywords

• |cerebral hemorrhage|pi3k/akt signal pathway|cell apoptosis|neuroinflammation