3D Bioprinting of Hydrogels for Cartilage Tissue Engineering
Jianghong Huang,
Jianyi Xiong,
Daping Wang,
Jun Zhang,
Lei Yang,
Shuqing Sun,
Yujie Liang
Affiliations
Jianghong Huang
Department of Orthopedics, Shenzhen Second People’s Hospital (Health Science Center, First Affiliated Hospital of Shenzhen University), Shenzhen 518035, China
Jianyi Xiong
Department of Orthopedics, Shenzhen Second People’s Hospital (Health Science Center, First Affiliated Hospital of Shenzhen University), Shenzhen 518035, China
Daping Wang
Department of Orthopedics, Shenzhen Second People’s Hospital (Health Science Center, First Affiliated Hospital of Shenzhen University), Shenzhen 518035, China
Jun Zhang
Tsinghua University Shenzhen International Graduate School, Shenzhen 518055, China
Lei Yang
Department of Orthopedics, Shenzhen Second People’s Hospital (Health Science Center, First Affiliated Hospital of Shenzhen University), Shenzhen 518035, China
Shuqing Sun
Institute of Biomedicine and Health Engineering, Tsinghua University Shenzhen International Graduate School, Shenzhen 518055, China
Yujie Liang
Department of Child and Adolescent Psychiatry, Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen 518020, China
Three-dimensional (3D) bioprinting is an emerging technology based on 3D digital imaging technology and multi-level continuous printing. The precise positioning of biological materials, seed cells, and biological factors, known as “additive biomanufacturing”, can provide personalized therapy strategies in regenerative medicine. Over the last two decades, 3D bioprinting hydrogels have significantly advanced the field of cartilage and bone tissue engineering. This article reviews the development of 3D bioprinting and its application in cartilage tissue engineering, followed by a discussion of the current challenges and prospects for 3D bioprinting. This review presents foundational information on the future optimization of the design and manufacturing process of 3D additive biomanufacturing.
