Pain Research and Management (Jan 2014)

Exogenous and Endogenous Opioid-Induced Pain Hypersensitivity in Different Rat Strains

  • Emilie Laboureyras,
  • Frédéric Aubrun,
  • Maud Monsaingeon,
  • Jean-Benoît Corcuff,
  • Jean-Paul Laulin,
  • Guy Simonnet

DOI
https://doi.org/10.1155/2014/285308
Journal volume & issue
Vol. 19, no. 4
pp. 191 – 197

Abstract

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BACKGROUND: Opioid-induced hyperalgesia (OIH) is a recognized complication of opioid use that may facilitate the development of exaggerated postoperative pain.