Modern directions of radionuclide diagnosis in patients with prostate cancer

Abstract

The review of the literature considers the key questions on the history of development and clinical application of modern methods for radionuclide diagnosis in patients with prostate cancer (PCa). The algorithm for making a diagnostic decision in patients with PCa takes into account the multidisciplinary approach to each stage of the process — from setting the primary diagnosis, staging, restaging to prescribing treatment procedures. In this context, nuclear medicine plays a key role when determining the activity of the disease characterizing the tumor in patients with a relapse of PCa from a functional point of view, as well as increasing the level of the prostate-specific antigen. However, further studies are needed to directly compare the new radioactive ligands in the same clinical settings and in the more numerous diagnostic groups that are needed to address the issue of finding the most sensitive markers of PCa and the conditions for their better use.

Keywords

• prostate cancer
• prostate-specific antigen
• radionuclide diagnosis
• review