Primary gastric inflammatory myofibroblastic tumor treated with non‐exposed endoscopic wall‐inversion surgery (NEWS): A case report and literature review
Yuka Masuda,
Yoshikazu Kanazawa,
Osamu Goto,
Daisuke Kakinuma,
Kazutoshi Higuchi,
Eriko Koizumi,
Ryosuke Nakata,
Nobuyuki Sakurazawa,
Fumihiko Ando,
Mikito Suzuki,
Toshiro Yoshiyuki,
Shunji Kato,
Ryuji Ohashi,
Mitsuru Kaise,
Katsuhiko Iwakiri,
Hiroshi Yoshida
Affiliations
Yuka Masuda
Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo Japan
Yoshikazu Kanazawa
Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo Japan
Osamu Goto
Department of Gastroenterology Nippon Medical School Hospital Tokyo Japan
Daisuke Kakinuma
Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo Japan
Kazutoshi Higuchi
Department of Gastroenterology Nippon Medical School Hospital Tokyo Japan
Eriko Koizumi
Department of Gastroenterology Nippon Medical School Hospital Tokyo Japan
Ryosuke Nakata
Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo Japan
Nobuyuki Sakurazawa
Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo Japan
Fumihiko Ando
Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo Japan
Mikito Suzuki
Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo Japan
Toshiro Yoshiyuki
Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo Japan
Shunji Kato
Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo Japan
Ryuji Ohashi
Department of Diagnostic Pathology Nippon Medical School Hospital Tokyo Japan
Mitsuru Kaise
Department of Gastroenterology Nippon Medical School Hospital Tokyo Japan
Katsuhiko Iwakiri
Department of Gastroenterology Nippon Medical School Hospital Tokyo Japan
Hiroshi Yoshida
Department of Gastrointestinal and Hepato‐biliary‐pancreatic Surgery Nippon Medical School Hospital Tokyo Japan
Abstract Inflammatory myofibroblastic tumor (IMT) is an intermediate malignancy with myofibroblast proliferation and inflammatory cell infiltration with malignant potential. Primary IMTs are predominantly reported in the lungs, while gastric IMTs are very rare. Therefore, no guidelines exist for the diagnosis and treatment of gastric IMTs. The present case is a 39‐year‐old man diagnosed with an asymptomatic gastric submucosal tumor. Considering the malignancy of the tumor, we selected non‐exposed endoscopic wall‐inversion surgery as the resection method and successfully performed local resection. Histopathological analysis showed myofibroblast proliferation and inflammatory cell infiltration, with a diagnosis of primary gastric IMT and negative resection margins. Immunohistochemical staining was negative for anaplastic lymphoma kinase. To the best of our knowledge, including our case, there have been 52 reported cases of primary gastric IMTs that have been treated, with several recurrent cases. In this study, we report the first case of local resection of gastric IMT using non‐exposed endoscopic wall‐inversion surgery, with a literature review.
