Cancers (Dec 2023)

Improved Prediction of Ovarian Cancer Using Ensemble Classifier and Shaply Explainable AI

  • Nihal Abuzinadah,
  • Sarath Kumar Posa,
  • Aisha Ahmed Alarfaj,
  • Ebtisam Abdullah Alabdulqader,
  • Muhammad Umer,
  • Tai-Hoon Kim,
  • Shtwai Alsubai,
  • Imran Ashraf

DOI
https://doi.org/10.3390/cancers15245793
Journal volume & issue
Vol. 15, no. 24
p. 5793

Abstract

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The importance of detecting and preventing ovarian cancer is of utmost significance for women’s overall health and wellness. Referred to as the “silent killer,” ovarian cancer exhibits inconspicuous symptoms during its initial phases, posing a challenge for timely identification. Identification of ovarian cancer during its advanced stages significantly diminishes the likelihood of effective treatment and survival. Regular screenings, such as pelvic exams, ultrasound, and blood tests for specific biomarkers, are essential tools for detecting the disease in its early, more treatable stages. This research makes use of the Soochow University ovarian cancer dataset, containing 50 features for the accurate detection of ovarian cancer. The proposed predictive model makes use of a stacked ensemble model, merging the strengths of bagging and boosting classifiers, and aims to enhance predictive accuracy and reliability. This combination harnesses the benefits of variance reduction and improved generalization, contributing to superior ovarian cancer prediction outcomes. The proposed model gives 96.87% accuracy, which is currently the highest model result obtained on this dataset so far using all features. Moreover, the outcomes are elucidated utilizing the explainable artificial intelligence method referred to as SHAPly. The excellence of the suggested model is demonstrated through a comparison of its performance with that of other cutting-edge models.

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