Adverse Drug Event From Artemether/lumefantrine Ingestion: Case Series

Abstract

We present rare cases of three adverse drug events from artemeter-Lumefantrine(AL) ingestion. This is an antimalaria combination therapy used in the management of malaria. Adverse reaction is rarely reported when using this drug. We report these cases of our patients who developed urticaria and bullae. One had hypotension few hours after taking AL. We report these cases to show that though rare, adverse drug event can occur in AL. Conclusion: Artemesinin combination therapy though safe in children, is not without adverse reaction.

Keywords

• arteme t e r -lumefantrine; children; adverse drug event