Hippocampal oxytocin receptors are necessary for discrimination of social stimuli

Tara Raam; Kathleen M. McAvoy; Antoine Besnard; Alexa H. Veenema; Amar Sahay

doi:10.1038/s41467-017-02173-0

Nature Communications (Dec 2017)

Hippocampal oxytocin receptors are necessary for discrimination of social stimuli

Tara Raam,
Kathleen M. McAvoy,
Antoine Besnard,
Alexa H. Veenema,
Amar Sahay

Affiliations

Tara Raam: Center for Regenerative Medicine, Massachusetts General Hospital
Kathleen M. McAvoy: Center for Regenerative Medicine, Massachusetts General Hospital
Antoine Besnard: Center for Regenerative Medicine, Massachusetts General Hospital
Alexa H. Veenema: Department of Psychology, Michigan State University
Amar Sahay: Center for Regenerative Medicine, Massachusetts General Hospital

DOI: https://doi.org/10.1038/s41467-017-02173-0
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 14

Abstract

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While oxytocin is known to be critical for social recognition, the functions of oxytocin receptors (Oxtrs) in the hippocampus are not known. This study shows that Oxtrs in anterior dentate gyrus and CA2/CA3 pyramidal cells recruit population-based coding to mediate discrimination of social stimuli.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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