Nature Communications (May 2021)

RTEL1 influences the abundance and localization of TERRA RNA

  • Fiorella Ghisays,
  • Aitor Garzia,
  • Hexiao Wang,
  • Claudia Canasto-Chibuque,
  • Marcel Hohl,
  • Sharon A. Savage,
  • Thomas Tuschl,
  • John H. J. Petrini

DOI
https://doi.org/10.1038/s41467-021-23299-2
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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Long non coding RNA TERRA transcripts can form R-loops at chromosome ends. Here, the authors reveal a role for the helicase RTEL in affecting TERRA levels and localization.