mSphere
(Feb 2021)
Human Cytomegalovirus UL7, miR-US5-1, and miR-UL112-3p Inactivation of FOXO3a Protects CD34
<sup>+</sup>
Hematopoietic Progenitor Cells from Apoptosis
Meaghan H. Hancock,
Lindsey B. Crawford,
Wilma Perez,
Hillary M. Struthers,
Jennifer Mitchell,
Patrizia Caposio
Affiliations
Meaghan H. Hancock
ORCiD Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA
Lindsey B. Crawford
ORCiD Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA
Wilma Perez
Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA
Hillary M. Struthers
Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA
Jennifer Mitchell
Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA
Patrizia Caposio
ORCiD Vaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, USA
DOI
https://doi.org/10.1128/mSphere.00986-20
Journal volume & issue
Vol. 6,
no. 1
Abstract
Read online
Human cytomegalovirus (HCMV) causes serious disease in immunocompromised individuals and is a significant problem during transplantation. The virus can establish a latent infection in CD34 +
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