Single-cell transcriptomics reveals a low CD8+ T cell infiltrating state mediated by fibroblasts in recurrent renal cell carcinoma

• Hui Han,
• Kang Ning,
• Ning Wang,
• Nan Jia,
• Yun Cao,
• Zhen Li,
• Yu-Lu Peng,
• Long-Bin Xiong,
• Zhao-Hui Zhou,
• Ze-Shen Wu,
• Min-Hua Deng,
• Wen-Su Wei,
• Xiang-Peng Zou,
• Zhi-Song He,
• Ji-Wei Huang,
• Jun-Hang Luo,
• Jian-Ye Liu,
• Sheng-Jie Guo,
• Pei Dong,
• Chun-Ping Yu,
• Fang-Jian Zhou,
• Zhi-Ling Zhang

Affiliations

Hui Han

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Kang Ning

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Ning Wang

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Nan Jia

Department of Nephrology, Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China

Yun Cao

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China

Zhen Li

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Yu-Lu Peng

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Long-Bin Xiong

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Zhao-Hui Zhou

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Ze-Shen Wu

Department of Urology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, Guangdong, China

Min-Hua Deng

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Wen-Su Wei

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Xiang-Peng Zou

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Zhi-Song He

Department of Urology, Peking University First Hospital, Beijing, China

Ji-Wei Huang

Department of Urology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, China

Jun-Hang Luo

Department of Urology, Sun Yat-sen University First Affiliated Hospital, Guangzhou, Guangdong, China

Jian-Ye Liu

Department of Urology, Central South University Third Xiangya Hospital, Changsha, Hunan, China

Sheng-Jie Guo

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Pei Dong

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Chun-Ping Yu

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Fang-Jian Zhou

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China

Zhi-Ling Zhang

Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China