Eco-friendly drugs induce cellular changes in colistin-resistant bacteria

Al-Khattaf Fatimah Saleh; Aloufi Abeer Salem; Moglad Ehssan; Ncibi Saida Sadek; Almuraikhi Nihal; Almaarik Basmah; Alaaullah Malek Hassan Ibrahim; Ali Rizwan; Abdalaziz Halah Salah Mohammed; Alaaullah Mohammed Hassan Ibrahim; Elsayim Rasha

doi:10.1515/gps-2024-0097

Green Processing and Synthesis (Oct 2024)

Eco-friendly drugs induce cellular changes in colistin-resistant bacteria

Al-Khattaf Fatimah Saleh,
Aloufi Abeer Salem,
Moglad Ehssan,
Ncibi Saida Sadek,
Almuraikhi Nihal,
Almaarik Basmah,
Alaaullah Malek Hassan Ibrahim,
Ali Rizwan,
Abdalaziz Halah Salah Mohammed,
Alaaullah Mohammed Hassan Ibrahim,
Elsayim Rasha

Affiliations

Al-Khattaf Fatimah Saleh: Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia
Aloufi Abeer Salem: Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia
Moglad Ehssan: Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Alkharj, 11942, Saudi Arabia
Ncibi Saida Sadek: Biology Department, Science College, Jazan University, Jazan, 45142, Saudi Arabia
Almuraikhi Nihal: Stem Cell Unit, Department of Anatomy, College of Medicine, King Saud University, Riyadh, 11461, Saudi Arabia
Almaarik Basmah: Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia
Alaaullah Malek Hassan Ibrahim: Emergency Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia
Ali Rizwan: Light and Electron Microscopy Unit, Medical Core Facility & Research Platforms, King Abdullah International Medical Research Center, National Guard Health Affairs, Riyadh, Saudi Arabia
Abdalaziz Halah Salah Mohammed: Department of Anesthesia Technology, College of Applied Sciences, Almaarefa University, Riyadh, Saudi Arabia
Alaaullah Mohammed Hassan Ibrahim: Infectious Department, Prince Mohammed Bin Nasser Hospital, Jazan, Saudi Arabia
Elsayim Rasha: Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia

DOI: https://doi.org/10.1515/gps-2024-0097
Journal volume & issue: Vol. 13, no. 1
pp. 711 – 8

Abstract

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As a last option, multidrug-resistant Gram-negative infections (caused by Enterobacteriaceae) are treated with the antibiotic colistin, also known as polymyxin E. Colistin-resistant superbugs predispose people to untreatable infections, possibly leading to a high mortality rate. This project aims to study the effect of Acacia nilotica aqueous extract and zinc oxide nanoparticles (ZnO-NPs) on colistin-resistant Klebsiella pneumonia (CRKP).

Published in Green Processing and Synthesis

ISSN: 2191-9542 (Print); 2191-9550 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Chemistry
Website: https://www.degruyter.com/view/j/gps

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