Materials (Oct 2022)

Bone Remodeling Interaction with Magnesium Alloy Implants Studied by SEM and EDX

  • Alexey Drobyshev,
  • Alexander Komissarov,
  • Nikolay Redko,
  • Zaira Gurganchova,
  • Eugene S. Statnik,
  • Viacheslav Bazhenov,
  • Iuliia Sadykova,
  • Andrey Miterev,
  • Igor Romanenko,
  • Oleg Yanushevich

DOI
https://doi.org/10.3390/ma15217529
Journal volume & issue
Vol. 15, no. 21
p. 7529

Abstract

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The development direction of bioresorbable fixing structures is currently very relevant because it corresponds to the priority areas in worldwide biotechnology development. Magnesium (Mg)-based alloys are gaining high levels of attention due to their promising potential use as the basis for fixating structures. These alloys can be an alternative to non-degradable metal implants in orthopedics, maxillofacial surgery, neurosurgery, and veterinary medicine. In our study, we formulated a Mg-2Zn-2Ga alloy, prepared pins, and analyzed their biodegradation level based on SEM (scanning electron microscopy) and EDX (energy-dispersive X-ray analysis) after carrying out an experimental study on rats. We assessed the resorption parameters 1, 3, and 6 months after surgery. In general, the biodegradation process was characterized by the systematic development of newly formed bone tissue. Our results showed that Mg-2Zn-2Ga magnesium alloys are suitable for clinical applications.

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