Case Reports in Cardiology (Jan 2018)

Safety and Efficacy of Triple Therapeutic Targets with Rivaroxaban after Acute Myocardial Infarction Complicated by Left Ventricular Thrombi in a Case of Nonvalvular Atrial Fibrillation

  • Francesco Summaria,
  • Gregory A. Sgueglia,
  • Fabrizio D’Errico,
  • Antonella De Santis,
  • Fabiana Piccioni,
  • Gaetano Gioffrè,
  • Achille Gaspardone

DOI
https://doi.org/10.1155/2018/6503435
Journal volume & issue
Vol. 2018

Abstract

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We present the complex case of a high-risk patient with nonvalvular atrial fibrillation, who experienced a non-ST elevation myocardial infarction complicated by left ventricular (LV) thrombi and underwent percutaneous coronary intervention with drug-eluting stent implantation. The patient was initially treated with short-term triple therapy including aspirin, clopidogrel, and rivaroxaban 15 mg/die. Following aspirin dropping one month after discharge, the patient continued on dual therapy with clopidogrel and rivaroxaban, and a clinical and imaging follow-up at 6 and 12 months confirmed the LV thrombi resolution, with no thromboembolic episodes and a good safety profile.