Polish Journal of Pathology (Apr 2023)

Recommendations of the Polish Association of Neuropathologists on performing post-mortem examination of the brain and spinal cord

  • Aleksandra Sejda,
  • Teresa Wierzba-Bobrowicz,
  • Sławomir Michalak,
  • Dariusz Adamek,
  • Jacek Gulczyński,
  • Maciej Ciołkowski,
  • Wiesława Grajkowska,
  • Ewa Iżycka-Świeszewska

DOI
https://doi.org/10.5114/pjp.2023.127231
Journal volume & issue
Vol. 74, no. 1
pp. 1 – 11

Abstract

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Neuropathological central nervous system (CNS) post-mortem examination is a highly specialistic element of the autopsy procedure with methodological specificity. Herein we propose updated recommendations for CNS autopsy for pathologists and neuropathologists. The protocol includes the compendium of neuroanatomy with current nomenclature, consecutive steps of gross examination, as well as appropriate sampling algorithms in different clinical and pathological settings. The significance of pathoclinical cooperation in differential diagnosis is exposed. We believe it is essential to create and promote the guidelines to improve the quality of CNS post-mortem examination at the national level.

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