Nature Communications (Jun 2021)

Glucose-oxidase like catalytic mechanism of noble metal nanozymes

  • Jinxing Chen,
  • Qian Ma,
  • Minghua Li,
  • Daiyong Chao,
  • Liang Huang,
  • Weiwei Wu,
  • Youxing Fang,
  • Shaojun Dong

DOI
https://doi.org/10.1038/s41467-021-23737-1
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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Gold nanoparticles (Au NPs) with enzyme-like activities are useful glucose oxidase mimics, but the insights into the mechanism of this reaction are limited. Here, the authors show that the process of glucose oxidation by Au NPs is analogous to the one catalysed by glucose oxidase, involving dehydrogenation and oxygen reduction to H2O2; and that other noble metal NPs also catalyse glucose dehydrogenation, but oxygen is preferably reduced to water.