Dataset of allele and genotype frequencies of the three functionally significant polymorphisms of the MMP genes in Russian patients with primary open-angle glaucoma, essential hypertension and peptic ulcer
Oksana Minyaylo,
Dina Starikova,
Maria Moskalenko,
Irina Ponomarenko,
Evgeny Reshetnikov,
Volodymyr Dvornyk,
Mikhail Churnosov
Affiliations
Oksana Minyaylo
Department of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, Russia
Dina Starikova
Department of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, Russia
Maria Moskalenko
Department of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, Russia
Irina Ponomarenko
Department of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, Russia
Evgeny Reshetnikov
Department of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, Russia; Corresponding author.
Volodymyr Dvornyk
Department of Life Sciences, College of Science and General Studies, Alfaisal University, Riyadh 11533, Saudi Arabia
Mikhail Churnosov
Department of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, Russia
Data on the allele and genotype frequencies of the three functionally significant single nucleotide polymorphisms (SNPs) of the matrix metalloproteinases (MMP) genes (rs1799750 MMP1, rs3918242 and rs17576 MMP9) in Russian patients with primary open-angle glaucoma (POAG), essential hypertension (EH) and peptic ulcer (PU) are presented. Association studies identified these SNPs as possible significant markers associated with many multifactorial disorders, including POAG, EH, and PU. The frequencies of alleles and genotypes of the three SNPs in Russian patients with POAG, EH, and PU were presented separately for the entire study sample, females, and males, respectively. The data can be used as a reference for the Russian population.
