circAPLP2 promotes colorectal cancer progression by upregulating HELLS by targeting miR-335-5p

Xiang Rui; Feng Min; Zhou Xin; Ma Lihong; Dong Ningfei

doi:10.1515/med-2021-0229

Open Medicine (Feb 2021)

circAPLP2 promotes colorectal cancer progression by upregulating HELLS by targeting miR-335-5p

Xiang Rui,
Feng Min,
Zhou Xin,
Ma Lihong,
Dong Ningfei

Affiliations

Xiang Rui: Department of Gastroenterology, West Hospital of Zibo Central Hospital, No. 10 Shanghai Road, Zhangdian District, Zibo, Shandong, 255000, China
Feng Min: Department of Gastroenterology, West Hospital of Zibo Central Hospital, No. 10 Shanghai Road, Zhangdian District, Zibo, Shandong, 255000, China
Zhou Xin: Department of Gastroenterology, West Hospital of Zibo Central Hospital, No. 10 Shanghai Road, Zhangdian District, Zibo, Shandong, 255000, China
Ma Lihong: Department of Gastroenterology, West Hospital of Zibo Central Hospital, No. 10 Shanghai Road, Zhangdian District, Zibo, Shandong, 255000, China
Dong Ningfei: Department of Gastroenterology, West Hospital of Zibo Central Hospital, No. 10 Shanghai Road, Zhangdian District, Zibo, Shandong, 255000, China

DOI: https://doi.org/10.1515/med-2021-0229
Journal volume & issue: Vol. 16, no. 1
pp. 338 – 350

Abstract

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Colorectal cancer (CRC) is one of the deadliest cancers in the world. Increasing evidence suggests that circular RNAs (circRNAs) are implicated in CRC pathogenesis. This study aimed to determine the role of circAPLP2 and explore a potential mechanism of circAPLP2 action in CRC.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

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Abstract

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