Journal of Advanced Research (Apr 2012)

A new convenient synthesis of 3-hetaryl-pyrazolo[5,1-c][1,2,4]triazines

  • Ahmad S. Shawali

DOI
https://doi.org/10.1016/j.jare.2011.07.004
Journal volume & issue
Vol. 3, no. 2
pp. 185 – 188

Abstract

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Reactions of enaminones 2 with diazotized 5-amino-3-phenylpyrazole provide a convenient route to 3-[(4,5-disubstituted-pyrazol-3-yl)carbonyl]-pyrazolo[5,1-c][1,2,4]triazines. Condensation of the latter with hydrazine hydrate yielded the title compounds. The structures of the compounds prepared were elucidated on the basis of their spectral and elemental analyses.

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