The efficacy and safety of genistein in the treatment of vasomotor symptoms in postmenopausal women (research review)

Abstract

The review discusses the efficacy and safety of phytoestrogens, preferably soy isoflavones in treating the menopausal syndrome symptoms. Particular attention is paid to the synthetic genistein. The highest genistein efficacy, when compared to other phytoestrogens is confirmed by comparative and placebo-controlled trials. However, prolonged use of genistein does not affect the proliferate processes in the endometrium and breast. Genistein can be considered a good alternative to hormone therapy when it is proved to be impossible or undesirable.

Keywords

• postmenopause
• phytoestrogens genistein
• hot flushes
• endometrial
• breast
• security