Cardiogenic pulmonary edema is a usual finding in a radiographic investigation, and unilateral pulmonary edema (UPE) is a possibility. We present a rare case of a 60-year-old female with acute coronary syndrome, acute mitral regurgitation (MR), and UPE secondary to papillary muscle rupture. The MR led to UPE that recovered after mitral valve replacement and a coronary artery bypass graft. Thus, awareness of early detection and management of UPE associated with MR can save a patient's life in life-threatening conditions.
