Cortical reliability amid noise and chaos

Max Nolte; Michael W. Reimann; James G. King; Henry Markram; Eilif B. Muller

doi:10.1038/s41467-019-11633-8

Nature Communications (Aug 2019)

Cortical reliability amid noise and chaos

Max Nolte,
Michael W. Reimann,
James G. King,
Henry Markram,
Eilif B. Muller

Affiliations

Max Nolte: Blue Brain Project, École Polytechnique Fédérale de Lausanne
Michael W. Reimann: Blue Brain Project, École Polytechnique Fédérale de Lausanne
James G. King: Blue Brain Project, École Polytechnique Fédérale de Lausanne
Henry Markram: Blue Brain Project, École Polytechnique Fédérale de Lausanne
Eilif B. Muller: Blue Brain Project, École Polytechnique Fédérale de Lausanne

DOI: https://doi.org/10.1038/s41467-019-11633-8
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 15

Abstract

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Whether cortical neurons can fire reliable spikes amid cellular noise and chaotic network dynamics remains debated. Here the authors simulate a detailed neocortical microcircuit model and show that noisy and chaotic cortical network dynamics are compatible with stimulus-evoked, millisecond spike-time reliability.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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