Nature Communications (Jan 2022)

Geminiviruses employ host DNA glycosylases to subvert DNA methylation-mediated defense

  • Xiaojian Gui,
  • Chang Liu,
  • Yijun Qi,
  • Xueping Zhou

DOI
https://doi.org/10.1038/s41467-022-28262-3
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Plants tightly regulate DNA methylation to regulate gene expression. Here, the authors show that the tomato yellow leaf curl China virus βC1 protein interacts with plant DNA glycosylases to promote demethylation of viral DNA and promote virulence.