Scientific Reports (May 2022)
Impact of obesity on cervical ossification of the posterior longitudinal ligament: a nationwide prospective study
- Kanji Mori,
- Toshitaka Yoshii,
- Satoru Egawa,
- Kenichiro Sakai,
- Kazuo Kusano,
- Shunji Tsutsui,
- Takashi Hirai,
- Yu Matsukura,
- Kanichiro Wada,
- Keiichi Katsumi,
- Masao Koda,
- Atsushi Kimura,
- Takeo Furuya,
- Satoshi Maki,
- Narihito Nagoshi,
- Norihiro Nishida,
- Yukitaka Nagamoto,
- Yasushi Oshima,
- Kei Ando,
- Hiroaki Nakashima,
- Masahiko Takahata,
- Hideaki Nakajima,
- Kazuma Murata,
- Masayuki Miyagi,
- Takashi Kaito,
- Kei Yamada,
- Tomohiro Banno,
- Satoshi Kato,
- Tetsuro Ohba,
- Satoshi Inami,
- Shunsuke Fujibayashi,
- Hiroyuki Katoh,
- Haruo Kanno,
- Hiroshi Taneichi,
- Shiro Imagama,
- Yoshiharu Kawaguchi,
- Katsushi Takeshita,
- Morio Matsumoto,
- Masashi Yamazaki,
- Atsushi Okawa
Affiliations
- Kanji Mori
- Department of Orthopaedic Surgery, Shiga University of Medical Science
- Toshitaka Yoshii
- Department of Orthopedic Surgery, Tokyo Medical and Dental University
- Satoru Egawa
- Department of Orthopedic Surgery, Tokyo Medical and Dental University
- Kenichiro Sakai
- Department of Orthopedic Surgery, Saiseikai Kawaguchi General Hospital
- Kazuo Kusano
- Department of Orthopedic Surgery, Kudanzaka Hospital
- Shunji Tsutsui
- Department of Orthopaedic Surgery, Wakayama Medical University
- Takashi Hirai
- Department of Orthopedic Surgery, Tokyo Medical and Dental University
- Yu Matsukura
- Department of Orthopedic Surgery, Tokyo Medical and Dental University
- Kanichiro Wada
- Department of Orthopedic Surgery, Hirosaki University Graduate School of Medicine
- Keiichi Katsumi
- Department of Orthopedic Surgery, Niigata University Medical and Dental General Hospital
- Masao Koda
- Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba
- Atsushi Kimura
- Department of Orthopedics, Jichi Medical University
- Takeo Furuya
- Department of Orthopedic Surgery, Chiba University Graduate School of Medicine
- Satoshi Maki
- Department of Orthopedic Surgery, Chiba University Graduate School of Medicine
- Narihito Nagoshi
- Department of Orthopaedic Surgery, Keio University School of Medicine
- Norihiro Nishida
- Department of Orthopedic Surgery, Yamaguchi University Graduate School, of Medicine
- Yukitaka Nagamoto
- Department of Orthopedic Surgery, Osaka Rosai Hospital
- Yasushi Oshima
- Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo
- Kei Ando
- Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine
- Hiroaki Nakashima
- Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine
- Masahiko Takahata
- Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
- Hideaki Nakajima
- Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui
- Kazuma Murata
- Department of Orthopedic Surgery, Tokyo Medical University
- Masayuki Miyagi
- Department of Orthopedic Surgery, Kitasato University, School of Medicine
- Takashi Kaito
- Department of Orthopedic Surgery, Graduate School of Medicine, Osaka University
- Kei Yamada
- Department of Orthopaedic Surgery, Kurume University School of Medicine
- Tomohiro Banno
- Department of Orthopedic Surgery, Hamamatsu University School of Medicine
- Satoshi Kato
- Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University
- Tetsuro Ohba
- Department of Orthopedic Surgery, University of Yamanashi
- Satoshi Inami
- Department of Orthopaedic Surgery, Dokkyo Medical University School of Medicine
- Shunsuke Fujibayashi
- Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University
- Hiroyuki Katoh
- Department of Orthopedic Surgery, Surgical Science, Tokai University School of Medicine
- Haruo Kanno
- Department of Orthopaedic Surgery, Tohoku University School of Medicine
- Hiroshi Taneichi
- Department of Orthopaedic Surgery, Dokkyo Medical University School of Medicine
- Shiro Imagama
- Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine
- Yoshiharu Kawaguchi
- Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama
- Katsushi Takeshita
- Department of Orthopedics, Jichi Medical University
- Morio Matsumoto
- Department of Orthopaedic Surgery, Keio University School of Medicine
- Masashi Yamazaki
- Department of Orthopedic Surgery, Faculty of Medicine, University of Tsukuba
- Atsushi Okawa
- Department of Orthopedic Surgery, Tokyo Medical and Dental University
- DOI
- https://doi.org/10.1038/s41598-022-12625-3
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 10
Abstract
Abstract Positive association between ossification of the posterior longitudinal ligament of the spine (OPLL) and obesity is widely recognized; however, few studies focused on the effects of obesity on treatment of cervical OPLL. The effects of obesity on surgical treatment of cervical OPLL were investigated by a Japanese nationwide, prospective study. Overall, 478 patients with cervical myelopathy due to OPLL were prospectively enrolled. To clarify the effects of obesity on the surgical treatment for cervical OPLL, patients were stratified into two groups, non-obese (< BMI 30.0 kg/m2) and obese (≥ BMI 30.0 kg/m2) groups. The mean age of the obese group was significantly younger than that of non-obese group. There were no significant differences between the two groups in other demographic information, medical history, and clinical and radiographical findings. Alternatively, the obese group had a significantly higher rate of surgical site infection (SSI) than that of non-obese group. Approach-specific analyses revealed that the SSI was significantly higher in the obese group than in the non-obese group. A logistic regression analysis revealed that age, BMI, and duration of symptoms were significant factors affecting the postoperative minimum clinically important difference success. The result of this study provides useful information for future cervical OPLL treatment.
