Synthesis, Spectroscopic, and Biological Studies on New Zirconium(IV) Porphyrins with Axial Ligand

Gauri D. Bajju; Gita Devi; Sapna Katoch; Madhulika Bhagat; Deepmala; Ashu; Sujata Kundan; Sunil Kumar Anand

doi:10.1155/2013/903616

Bioinorganic Chemistry and Applications (Jan 2013)

Synthesis, Spectroscopic, and Biological Studies on New Zirconium(IV) Porphyrins with Axial Ligand

Gauri D. Bajju,
Gita Devi,
Sapna Katoch,
Madhulika Bhagat,
Deepmala,
Ashu,
Sujata Kundan,
Sunil Kumar Anand

Affiliations

Gauri D. Bajju: P.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, India
Gita Devi: P.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, India
Sapna Katoch: P.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, India
Madhulika Bhagat: School of Biotechnology, University of Jammu, Jammu, Jammu and Kashmir 180006, India
Deepmala: P.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, India
Ashu: P.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, India
Sujata Kundan: P.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, India
Sunil Kumar Anand: P.G. Department of Chemistry, University of Jammu, Jammu, Jammu and Kashmir 180006, India

DOI: https://doi.org/10.1155/2013/903616
Journal volume & issue: Vol. 2013

Abstract

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A series of parasubstituted tetraphenylporphyrin zirconium(IV) salicylate complexes (SA/5-SSAZr(IV)RTPP, R = p-H, p-CH3, p-NO2, p-Cl, SA = salicylate, and 5-SSA = 5-sulfosalicylate) have been synthesized, and the spectral properties of free base porphyrins, their corresponding metallated, and axially ligated zirconium(IV) porphyrin compounds were compared with each other. A detailed analysis of ultraviolet-visible (UV-vis), proton nulcear magnetic resonance (1H NMR) spectroscopy, infrared (IR) spectroscopy, and elemental analysis suggested the transformation from free base porphyrins to zirconium(IV) porphyrins. The ability of the metal in this complex for extra coordination of solvent molecules was confirmed by ESI-MS spectra. Besides the fluorescence, cyclic voltammetry, and thermogravimetric studies, the complexes were also screened for antimicrobial and anticancer activities. Among all the complexes, 5-SSAZr(p-NO2TPP) shows high antibacterial activity.

Published in Bioinorganic Chemistry and Applications

ISSN: 1565-3633 (Print); 1687-479X (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Technology: Chemical technology: Biotechnology; Science: Chemistry: Inorganic chemistry
Website: https://www.hindawi.com/journals/bca/

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