Data in Brief (Jun 2018)

Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel

  • Eliza Li Shan Fong,
  • Tan Boon Toh,
  • Quy Xiao Xuan Lin,
  • Zheng Liu,
  • Lissa Hooi,
  • Masturah Bte Mohd Abdul Rashid,
  • Touati Benoukraf,
  • Edward Kai-Hua Chow,
  • The Hung Huynh,
  • Hanry Yu

Journal volume & issue
Vol. 18
pp. 594 – 606

Abstract

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This data article presents datasets associated with the research article entitled “Generation of matched patient-derived xenograft in vitro–in vivo models using 3D macroporous hydrogels for the study of liver cancer” (Fong et al., 2018) [1]. A three-dimensional macroporous sponge system was used to generate in vitro counterparts to various hepatocellular carcinoma patient-derived xenograft (HCC-PDX) lines. This article describes the viability, proliferative capacity and molecular features (genomic and transcriptomic profiles) of the cultured HCC-PDX cells. The sequencing datasets are made publicly available to enable critical or further analyzes.