Perioperative Medicine (Mar 2025)

Intraoperative fentanyl in endoscopic procedures and their impact on PACU time and costs

  • Miho Akabane,
  • Kelsey Kukuruza,
  • Timothy Angelotti,
  • Subhas Banerjee,
  • Kazuo Ando

DOI
https://doi.org/10.1186/s13741-025-00515-x
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 8

Abstract

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Abstract Background Extended stays in the postanesthesia care unit (PACU) pose challenges in high-volume endoscopies. This study investigates the impact of intraoperative fentanyl use on PACU duration, postoperative pain, and financial implications in outpatient endoscopy. Method A retrospective analysis of upper/lower endoscopies at our facility (2020–2022) was conducted, focusing on the relationship between fentanyl use, PACU duration, and pain scales. Financial impacts were also assessed. Results Among 11,488 patients, 5787 (50.4%) received intraoperative fentanyl, and 5225 (45.5%) had a long stay at PACU (> 50 min). A larger proportion of patients in the long-stay group (> 50 min) received fentanyl (56.3% vs. 45.4%, P 5 in 3.6% vs. 1.2%, P 5: 2.8% for fentanyl users vs. 2.2% for nonusers). Furthermore, most patients reported no pain post-surgery (93.0% for fentanyl users vs. 95.2% for nonusers). Fentanyl recipients did not have shorter PACU stays within any pain scale category. Financial simulations suggest that fentanyl-free anesthesia management could notably decrease the financial burden within endoscopy operations. Specifically, our institution could have realized an annual saving of at least US $100,308. Conclusion Intraoperative fentanyl increases PACU duration by approximately 4 min per patient in endoscopies, without markedly improving pain management. Avoiding fentanyl could lead to significant time and cost savings.

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