Nature Communications (Feb 2021)

Auxin-mediated protein depletion for metabolic engineering in terpene-producing yeast

  • Zeyu Lu,
  • Bingyin Peng,
  • Birgitta E. Ebert,
  • Geoff Dumsday,
  • Claudia E. Vickers

DOI
https://doi.org/10.1038/s41467-021-21313-1
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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Loss-of-function experiments are used in metabolic engineering to understand and optimise metabolism. Here, the authors apply auxin inducible protein degradation to test different metabolic engineering strategies for improved terpenoid production in yeast.