Excipients used in nano-technology assisted drug delivery systems

Abstract

The overall therapeutic benefit of an active pharmaceutical ingredient (API) is dependent on its potency and efficacy to deliver to the site of action. Drug delivery systems enable optimization of the latter by altering the physicochemical and/or biopharmaceutical properties of the API(s). Application of nanotechnology for the prevention and the treatment of diseases has provided a wider platform for delivery of ‘difficult to deliver’ APIs. This increasing utilization of nanotechnology assisted drug delivery systems (NADDS) has demonstrated wide-ranging benefits, from improvement in oral bioavailability to targeting of drug to specific tissues.