Emerging invasive nonvaccine pneumoccocal serotype 25

Abstract

Streptococcus pneumoniae (pneumococcus) is a bacterial pathogen that causes invasive infections, including septicemia and meningitis, as well as noninvasive infections such as community-acquired pneumonia, sinusitis and acute otitis media. Vaccination with pneumococcal conjugate vaccine (PCV7) has significantly reduced the burden of pneumococcal disease; however it targets only seven of the more than 92 pneumococcal serotypes. Concerns have been raised that nonvaccine serotypes could increase in prevalence and reduce the benefits of vaccination. We report one case with invasive nonvaccine serotype 25 that presented with meningitis.