European Journal of Case Reports in Internal Medicine (Jan 2024)

Acute thrombocytosis in a patient treated with ertapenem

  • Edward K. Sarfo,
  • Jennifer L. Dziemianko,
  • Thomas Chen,
  • Kosuke K. Iwaki

DOI
https://doi.org/10.12890/2024_004283

Abstract

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Ertapenem, a carbapenem-type beta-lactam antibiotic, demonstrates broad-spectrum efficacy against a wide range of Gram-positive and Gram-negative bacteria, including aerobes and anaerobes. Importantly, it demonstrates resistance to virtually all beta-lactamases, including the extended spectrum beta-lactamases (ESBLs). Haematologic complications such as thrombocytosis, haemolysis, anaemia, and neutropenia are infrequent side effects associated with this drug. In this report, we present a rare case of ertapenem-induced thrombocytosis in a 62-year-old female patient who was admitted for a complicated urinary tract infection caused by Escherichia coli.

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