Cardiovascular diseases: Interplay of epigenetics

Abstract

Several association studies have been carried out to elucidate the role of genetic variants in cardiovascular diseases (CVDs), while studies on the epigenome regulating gene expression changes are helping to understand the development of disease and factors promoting such changes. This review summarizes the different epigenetic aspects involved in cardiac development and disease along with current therapeutic interventions.

Keywords

• cardiovascular disease
• epigenetic
• factors
• therapeutic